PUBLICATIONS
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Selenium reduction of ubiquinone via SQOR suppresses ferroptosis
Lee, N., Park, S.J., Lange, M., Tseyang, T., Doshi, M., Kwon, T.Y., Song, Y., Greer, P.L., Olzmann, J.A., Spinelli, J., Kim, D. (Accepted in Principle)
65
Small molecule correctors divert CFTR-F508del from ERAD by stabilizing sequential folding states
Riepe, C., Wachalska, M., Deol, K.K. Amaya, K. Porteus, M.H., Olzmann, J.A., Kopito, R.R. Molecular Biology of the Cell. Online ahead of print.
64
Lipid quality control and ferroptosis: From concept to mechanism
Li, Z.*, Lange, M.*, Dixon, S.J., Olzmann, J.A. Annual Review of Biochemistry. Online ahead of print.
63
A cell cycle-dependent ferroptosis sensitivity switch governed by EMP2
Rodencal, J., Stahlhut, C., Kim, N., Li, V.L., He, A., Lange, M., He, J., Tarangelo, A., Schafer, Z.T., Olzmann, J.A., Sage, J., Long, J.Z., Beltran, P., Dixon, S.J.
Cell Chemical Biology. 31, 1-15. Online ahead of print.
62
Parallel CRISPR-Cas9 screens reveal mechanisms of PLIN2 and lipid droplet regulation
Roberts, M.A., Deol, K.K., Lange, M., Leto, D., Mathiowetz, A.J., Stevenson, J., Hashemi, S.H., Morgens, D.W., Easter, E., Heydari, K., Nalls, M.A., Bassik, M.C., Kampmann, M., Kopito, R.R., Faghri, F., Olzmann, J.A.
Developmental Cell. (2023) S1534-5807(23)00331-3.
61
Identification of structurally diverse FSP1 inhibitors that sensitize cancer cells to ferroptosis
Hendricks, J.M., Doubravsky, C.E., Wehri, E., Li, Z., Roberts, M.A., Deol, K.K., Lange, M., Lasheras-Otero, I., Momper, J.D., Dixon, S.J., Bersuker, K., Schlatetzky, J.#, Olzmann, J.A.#
Cell Chemical Biology. (2023) 4;S2451-9456(23)00114-9.
bioRxiv link posted 12.14.2022
– Featured in Preview by da Silva and Friedmann Angeli (Cell Chem Biol 2023)
60
Protocol for performing pooled CRISPR-Cas9 loss of function screens to identify genetic modifiers
Mathiowetz, A.J.*, Roberts, M.A.*, Morgens, D.W., Olzmann, J.A.#, Li, Z.#
STAR Protocols. (2023) 4(2):102201.
59
Hydropersulfides are endogenous antioxidants that inhibit ferroptosis
Lange, M. and Olzmann, J.A.
Cell Chemical Biology. (2022) 29(12):1661-1663.
58
A genome-wide CRISPR screen implicates plasma membrane asymmetry in exogenous C6-ceramide toxicity
Morris, S.N.S., Deol, K.K., Lange, M., Olzmann, J.A.
Biology Open. (2022) 11(12):bio059695.
57
VPS13A and VPS13C influence lipid droplet abundance
Chen, S.*, Roberts, M.A.*, Chen, C.Y., Markmiller, S., Wei, H.G., Yeo, G.W., Granneman, J.G., Olzmann, J.A.#, Ferro-Novick, S.#
Contact. (2022) 5, 1-7.
56
Context-dependent regulation of ferroptosis sensitivity
Magtanong, L., Mueller, G.D., Williams, K.J., TKO Lab, Andrews, B., Boone, C., Moffat, J., Olzmann, J.A., Bensinger, S.J., Dixon, S.J.
Cell Chemical Biology. (2022) S2451-9456(22)00236-7.
55
End of the road: From the ER to the proteasome
Olzmann, J.A.
Nature Review of Molecular and Cell Biology. (2022) 23(8):520.
54
Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability
Li., Z., Ferguson, L., Deol, K.K., Roberts, M.A., Magtanong, L., Hendricks, J.M., Mousa, G.A., Kilinc, S., Schaefer, K., Wells, J.A., Bassik, M.C., Goga, A., Dixon, S.J., Ingolia, N., Olzmann, J.A.
Nature Chemical Biology. (2022) 18(7):751-761.
53
The Lipid Droplet Knowledge Portal: A resource for systematic analyses of lipid droplet biology
Mejhert N., Gabriel, K.R., Frendo-Cumbo, S., Krahmer, N., Song, J., Kuruvilla, L., Chitraju, C., Boland, S., Jang, D.K., von Grotthuss, M., Costanzo, M.C., Ryden, M., Olzmann, J.A., Flannick, J., Burtt, N.P., Farese, R.V., Walther, T.C.
Developmental Cell. (2022) 57, 387–397.
52
Olzmann, J.A., Fendt, S.M., Shah, Y., Vousden, K., Chandel, N., Horng, T., Danial, N., Tu, B., Christofk, H., Vander Heiden, M.G., Wellen, K.
Molecular Cell. (2021) 81(18):3659-3664.
51
Ending on a sour note: Lipids orchestrate ferroptosis in cancer
Lange, M., Olzmann, J.A.
Cell Metabolism. (2021) 33(8):1507-1509.
50
Peterson, C.W.H.*, Deol, K.K.*, To, M., Olzmann, J.A.
STAR Protocols. (2021) 5;2(2):100579.
49
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
Klionsky, D. ... Olzmann, J.A., et al.
Autophagy. (2021) 17(1):1-382.
48
Diversity through equity and inclusion: The responsibility belongs to all of us
Olzmann, J.A.
Molecular Biology of the Cell. (2020) 31(25):2757-2760.
47
Protein quality control and lipid droplet metabolism
Roberts, M.A., Olzmann, J.A.
Annual Review of Cell Developmental Biology. (2020) 36:115-139.
46
Organelle biogenesis: ER shape influences lipid droplet nucleation
Roberts, M.A., Segura-Roman, A., Olzmann, J.A.
Current Biology. (2020) 30(13), R770–R773.
45
Liang, J.R.*, Lingeman, E.*, Luong, T., Ahmed, S., Nguyen, T., Olzmann, J.A., Corn, J.
Cell. (2020) 180, 1–18.
– Featured in Research Highlight by Paulina Strzyz (Nat. Rev. Mol. Cell Biol. 2020)
– Featured in Spotlight by Maurizio Molinari (Mol. Cell. 2020)
44
Li, Z., Morris, S.N.S., Olzmann, J.A.
Nature Chemical Biology. (2020) 16(2):111-112.
43
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
Bersuker, K., Hendricks, J., Li, Z., Magtanong, L., Ford, B., Tang, P.H., Roberts, M.A., Tong, B., Maimone, T.J., Zoncu, R., Nomura, D.K., Bassik, M.C., Dixon, S.J., Olzmann, J.A.
Nature. (2019) 575(7784):688-692.
– Featured in News & Views by Brent Stockwell (Nature 2019)
– Featured in Research Highlight by Grant Miura (Nat. Chem. Biol. 2019)
– Featured in Research Highlight by Liang et al. (Cell Res. 2019)
– Featured in Preview by Massimo Santoro (Cell Metab. 2020)
– Featured in Viewpoint by Kamyar Hadian (Biochemistry 2020)
42
Chung C.Y.S., Shin, H.R., Berdan, C.A., Ford, B., Ward, C.C., Olzmann J.A., Zoncu, R., Nomura, D.K.
Nature Chemical Biology. (2019) 15(8):776-785.
41
A tense situation: Maintaining ER homeostasis during lipid droplet budding
Morris, S.N.S., Olzmann, J.A.
Developmental Cell. (2019) 50, 1-2.
40
Harnessing the anti-cancer natural product nimbolide for targeted protein degradation
Spradlin, J.N., Hu, X., Ward, C.C., Brittain, S.M., Jones, M.D., Ou, L., To, M., Proudfoot, A., Ornelas, E., Woldegiorgis, M., Olzmann, J.A., Bussiere, D.E., Thomas, J.R., Tallarico, J.A., McKenna, J.M., Schirle, M., Maimone, T.J., Nomura, D.K.
Nature Chemical Biology. (2019) 15(7):747-755.
– Featured in News & Views by Brand and Winter (Nat. Chem. Biol. 2019)
39
Identification of lipid droplet proteomes by proximity labeling proteomics using APEX2
Bersuker, K., Olzmann, J.A.
Methods Molecular Biology. - Proximity Labeling. (2019) 57-72.
38
Berdan, C.A., Ho, R., Lehtola, H.S., To, M., Hu, X., Huffman, T.R., Petri, Y., Altobelli, C.R., Demeulenaere, S.G., Olzmann, J.A., Maimone, T.J., Nomura, D.K.
Cell Chemical Biology. (2019) 26(7):1027-1035.
37
Getting a handle on lipid droplets: Insights into ER-lipid droplet tethering
Nguyen, T., Olzmann J.A.
Journal of Cell Biology. (2019) 218(4):1089-1091.
36
Exogenous monounsaturated fatty acids suppress non-apoptotic cell death
Magtanong, L., Ko, P.J., To, M., Cao, J.Y., Tarangelo, A.N., Ward, C., Nomura, D.K., Olzmann, J.A., Dixon, S.
Cell Chemical Biology. (2019) 26, 420–432.
– Featured in Preview by Undurti Das (Cell Chem. Biol., 26, 309-311)
35
Dynamics and functions of lipid droplets
Olzmann, J.A., Carvalho, P.
Nature Review of Molecular and Cell Biology. (2019) 20(3): 137-155.
34
A proteomic map to navigate subcellular reorganization in fatty liver disease
Li, Z., Olzmann, J.A.
Developmental Cell. (2018) 47, 139-141.
33
In close proximity: The lipid droplet proteome and crosstalk with the ER
Bersuker, K, Olzmann, J.A.
Contact. (2018) (1), 1-3.
32
Huang, E.Y.*, To, M.*, Tran, E., Dionisio, L., Cho, H.J., Baney, K.L.M., Pataki, C.I., Olzmann, J.A.
Molecular Biology of the Cell. (2018) 29(9), 1021-1030.
31
Bersuker, K., Peterson, C.W., To, M., Sahl, S.J., Savikhin, V., Grossman, E.A., Nomura, D.K., Olzmann, J.A.
Developmental Cell. (2018) 44, 97-112.
30
Anderson, K.E., To, M., Olzmann, J.A., Nomura, D.K.
ACS Chemical Biology. (2017) 12(10), 2522-2528.
29
Lipid droplets and lipotoxicity during autophagy
Nguyen, T.B., Olzmann, J.A.
Autophagy. (2017) 13:11, 2002-2003.
28
Nguyen, T.B., Louie, S.M., Daniele, J., Tran, Q., Dillin, A., Zoncu, R., Nomura, D.K., Olzmann, J.A.
Developmental Cell. (2017) 42, 9–21.
– Featured in Preview by Klecker et al. (Dev. Cell 41, 1-2)
– Featured in Comment by Li et al. (Autophagy 13, 1995-1997)
27
Bersuker, K., Olzmann, J.A.
BBA - Molecular and Cell Biology of Lipids. (2017) 1862(10 Pt B), 1166-1177.
26
Hwang, J., Walczak, C.P., Shaler, T.A., Olzmann, J.A., Zhang, L., Elias, J.E., Kopito, R.R.
Journal of Biological Chemistry. (2017) 292, 9104-9116.
25
Bateman, L.A.*, Nguyen, T.B.*, Roberts, A.M.*, Miyamoto, D.K., Ku, W.M., Huffman, T.R., Petri, Y., Heslin, M.J., Contreras, C.M., Skibola, C.F., Olzmann, J.A.#, Nomura, D.K.#
# indicates co-corresponding authors
Chemical Communications. (2017) Jun 29;53(53), 7234-7237.
24
To, M.*, Peterson, C.W.*, Roberts, M.A., Counihan, J.L., Wu, T.T., Forster, M.S., Nomura, D.K., Olzmann, J.A.
Molecular Biology of the Cell. (2017) (28), 270-284.
23
Endoplasmic reticulum-associated degradation and lipid homeostasis
Stevenson, J.*, Huang, E.Y.*, Olzmann, J.A.
Annual Review of Nutrition. (2016) 36, 17.1–17.32.
22
A polyubiquitin chain reaction: Parkin recruitment to damaged mitochondria
Riley, B.E., Olzmann, J.A.
PLOS Genet. (2015) 11(1), e1004952.
21
Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover
Olzmann, J.A., Richter, C.R., Kopito, R.R.
Proc. Natl. Acad. Sci. (2013) 110(4), 1345-50.
20
The mammalian endoplasmic reticulum-associated degradation system
Olzmann, J.A., Kopito, R.R., Christianson, J.C.
Cold Spring Harb. Perspect. Biol. (2013) cshperspect.a013185v1. 1;5(9), pii: a013185.
19
Unassembled CD147 is an endogenous ER-associated degradation (ERAD) substrate
Tyler, R.E., Pearce, M.M.P., Shaler, T.A., Olzmann, J.A., Greenblatt, E.J., Kopito, R.R.
Molecular Biology of the Cell. (2012) 23(24), 4668-78.
18
Making the cut: Intramembrane cleavage by a rhomboid protease promotes ERAD
Greenblatt, E.J., Olzmann, J.A., Kopito, R.R.
Nature Structural and Molecular Biology. (2012) 19(10), 979-981.
17
Defining human ERAD networks through an integrated mapping strategy
Christianson, J.C.*, Olzmann, J.A.*, Shaler, T.A., Sowa, M.E., Bennett, E.J., Richter, C.M., Tyler, R.E., Greenblatt, E.J., Harper, J.W., Kopito, R.R.
* These authors contributed equally
Nature Cell Biology. (2012) 14(1), 93-105.
– Featured in News and Views by Thibault Mayor (Nat Cell Biol 14(1), 46-47)
16
Greenblatt, E.J., Olzmann, J.A., Kopito, R.R.
Nature Structural and Molecular Biology. (2011) 18(10), 1147-1152.
15
Lee, S.M., Olzmann, J.A., Chin, L.S., Li, L.
Journal of Cell Science. (2011) 124, 3319-3331.
14
Lipid droplets are dispensable for endoplasmic reticulum-associated degradation
Kopito, R.R., Olzmann, J.A.
Journal of Biological Chemistry. (2011) 286, 27872-27874.
13
Parkin-mediated ubiquitin signaling in aggresome formation and autophagy
Chin, L.S., Olzmann, J.A., Li, L.
Biochem. Soc. Trans. (2010) 48(1), 144-149.
12
Wang, Y., Pearce, M.M., Sliter, D.A., Olzmann, J.A., Christianson, J.C., Kopito, R.R., Boeckmann, S., Gagen, C., Leichner, G.S., Roitelman, J., Wojcikiewicz, R.J.
Biochim. Biophys. Acta. (2009) 1793(11), 1710-8.
11
Kim, B.Y., Olzmann, J.A., Choi, S.I., Ahn, S.Y., Kim, T.I., Cho, H.S., Suh, H., Kim, E.K.
Journal of Biological Chemistry. (2009) 284,19580-19591.
10
Aggresome formation and neurodegenerative diseases: therapeutic implications
Olzmann, J.A., Li, L., Chin, L.S.
Current Medicinal Chemistry. (200) 15(1), 47-60.
9
Olzmann, J.A., Chin, L.S.
Autophagy. (200) 4(1), 85-87.
8
Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding HDAC6
Olzmann, J.A., Li, L., Chudaev, M., Perez, F.A., Palmiter, R. D., Chin, L.S.
Journal of Cell Biology. (2007) 178, 1025-1038.
7
Pridgeon, J.W.*, Olzmann, J.A.*, Chin, L.S., Li, L.
* These authors contributed equally
PLOS Biology. (2007) 5, e172.
– Featured in Primer by Kroemer and Blomgren (PLOS Biol 5(7):e206)
6
Kim, B.Y.*, Olzmann, J.A.*, Barsh, G.S., Chin, L.S., Li, L.
* These authors contributed equally
Molecular Biology of the Cell. (2007) 18, 1129-1142.
5
Olzmann, J.A., Bordelon, J.R., Muly, E.C., Rees, H.D., Levey, A.I., Li, L, Chin, L.S.
Journal of Comparative Neurology. (2007) 500, 585-599.
4
Oxidative damage of DJ-1 is linked to sporadic Parkinson's and Alzheimer's diseases
Choi, J., Sullards, C. M., Olzmann, J. A., Rees, H. D., Weintraub, S. T., Bostwick, D. E., Gearing, M., Levey, A. I., Chin, L. S., Li, L.
Journal of Biological Chemistry. (2006) 281, 10816-24.
3
Uncoupling proteins prevent glucose-induced neuronal oxidative stress and programmed cell death
Vincent, A. M., Olzmann, J. A., Brownlee, M., Sivitz, W. I., and Russell, J. W.
Diabetes. (2004) 53, 726-734.
2
Familial Parkinson's disease-associated L166P mutation disrupts DJ-1 protein folding and function
Olzmann, J.A., Brown, K., Wilkinson, K. D., Rees, H. D., Huai, Q., Ke, H., Levey, A. I., Li, L., and Chin, L. S.
Journal of Biological Chemistry. (2004) 279, 8506-8515.
1
High glucose-induced oxidative stress and mitochondrial dysfunction in neurons
Russell, J. W., Golovoy, D., Vincent, A. M., Mahendru, P., Olzmann, J.A., Mentzer, A., and Feldman, E. L.
FASEB Journal. (2002) 16, 1738-1748.